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PositiveID Corp (OTCMKTS:PSID) Commences Testing Assays On Breadboard PCR

PositiveID Corp (OTCMKTS:PSID) reported considerable progress in the development of its Firefly Dx system. It has successfully created the structure of its breadboard PCR chip. Now, it has entered into next stage of testing assays to prove its objective of achieving ‘PCR results’ in less than twenty minutes at standard laboratory volumes. The existing system requires the laboratory-based equipment and takes hours or even days to deliver results. PositiveID will report the testing results as soon as it is completed in the next few months.

The details of the system

PositiveID Corp (OTCMKTS:PSID) will operate thermal cycling process at a rapid rate, with forty PCR cycles of cooling and heating. The Firefly DX system utilizes industry standard ’25-30’ uL reaction volumes. Therefore, it expects that existing FDA-approved PCR assays can be ported to the system quickly. It will not only reduce development time but will also minimize expenses.

The tasks

The first task of PositiveID’s biology and engineering teams will be to finish the evaluation process of PCR design and updated sample preparation to be integrated into the final process of the Firefly Dx cartridge. PositiveID Corp (OTCMKTS:PSID) will also work on optimization of the lyophilized PCR reagents. After the validation, the design will be integrated into a disposable cartridge. It will then be optimized and evaluated to operate automatically on the new platform.

The management view

The creation of the breadboard PCR is a major accomplishment. It was one of the crucial parts, with the highest risk in the development process. William J. Caragol, the CEO of PositiveID Corp (OTCMKTS:PSID) said that company is confident about design and the next goal is to achieve real-time PCR results at standard volumes in few minutes. Itwould be a landmark in entering into the multi-billion dollar PCR market. The Firefly DX system will combine real-time PCR analysis, sample Iysis, automated chain of custody and electronic reporting of results, with rooted RFID chip in disposable cartridges.

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